Мойзес Веласкес-Манофф - Эпидемия стерильности

Susan E. Erdman, Teoflos Poutahidis. “Cancer Inflammation and Regulatory T-cells”. International Journal of Cancer 127, № 4 (2010); Susan E. Erdman et al. “Unifying Roles for Regulatory T-cells and Inflammation in Cancer”. International Journal of Cancer 126, № 7 (2010).

P. M. Rothwell et al. “Effect of Daily Aspirin on Long-term Risk of Death Due to Cancer: Analysis of Individual Patient Data from Randomised Trials”. Lancet 377, № 9759 (2011).

Edward F. McCarthy. “The Toxins of William B. Coley and the Treatment of Bone and Soft-tissue Sarcomas”. Iowa Orthopaedic Journal 26 (2006).

U. Hobohm. “Fever Therapy Revisited”. British Journal of Cancer 92, № 3 (2005).

K. F. Kölmel et al. “Infections and Melanoma Risk: Results of a Multicentre EORTC Case-control Study”. Melanoma Research 9, № 5 (1999).

C. Garbe, U. Leiter. “Melanoma Epidemiology and Trends”. Clinical Dermatology 27, № 1 (2009).

B. Krone, J. M. Grange. “Melanoma, Darwinian Medicine and the Inner World”. Journal of Cancer Research and Clinical Oncology 136, № 12 (2010).

Ellen T. Chang et al. “Childhood Social Environment and Hodgkin’s Lymphoma: New Findings from a Population-based Case-control Study”. Cancer Epidemiology, Biomarkers & Prevention 13, № 8 (2004).

Mel Greaves. “Infection, Immune Responses and the Etiology of Childhood Leukemia”. Nature Reviews Cancer 6, № 3 (2006).

C. Gilham et al. “Day Care in Infancy and Risk of Childhood Acute Lymphoblastic Leukemia: Findings from UK Case-control Study”. British Medical Journal (Clinical Research Ed.) 330, № 7503 (2005).

S. J. O’Keefe et al. “Rarity of Colon Cancer in Africans Is Associated with Low Animal Product Consumption, Not Fiber”. American Journal of Gastroenterology 94, № 5 (1999).

S. J. O’Keefe et al. “Products of the Colonic Microbiota Mediate the Effects of Diet on Colon Cancer Risk”. Journal of Nutrition 139, № 11 (2009).

J. B. Greer, S. J. O’Keefe. “Microbial Induction of Immunity, Inflammation, and Cancer”. Frontiers in Physiology 1 (2011).

M. El-Zein et al. “History of Asthma or Eczema and Cancer Risk among Men: A Population-based Case-control Study in Montreal, Quebec, Canada”. Annals of Allergy, Asthma & Immunology 104, № 5 (2010).

Fanny Legrand et al. “Human Eosinophils Expert TNF-α and Granzyme A-Mediated Tumoricidal Activity toward Colon Carcinoma Cells”. Journal of Immunology 185, № 12 (2010).

A. E. Prizment et al. “Inverse Association of Eosinophil Count with Colorectal Cancer Incidence: Atherosclerosis Risk in Communities Study”. Cancer Epidemiology Biomarkers and Prevention 20, № 9 (2011).

У носителей вариантов генов, повышающих уровень гормонов роста, более высокий риск развития онкологических заболеваний. Elizabeth C. Leroy et al. “Genes in the Insulin and Insulin-like Growth Factor Pathway and Odds of Metachronous Colorectal Neoplasia”. Human Genetics 129, № 5 (2011). С другой стороны, среди людей с нарушенной сигнализацией гормонов роста рак встречается поразительно редко. В ходе исследования жителей отдаленных эквадорских деревень, у которых произошла мутация рецептора гормона роста (именно поэтому они маленького роста), было установлено, что они не страдают онкологическими заболеваниями. Jaime Guevara-Aguirre et al. “Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-aging Signaling, Cancer, and Diabetes in Humans”. Science: Translational Medicine 3, № 70 (2011).

Многие представленные здесь идеи в отношении рака и уровня гормонов взяты из: Tessa M. Pollard. Western Diseases: An Evolutionary Perspective. Cambridge and New York: Cambridge University Press, 2008, 75–98. Информацию об уровне гормонов у мужчин в разных условиях см.: P. T. Ellison et al. “Population Variation in Age-related Decline in Male Salivary Testosterone”. Human Reproduction 17, № 12 (2002).

Превосходный обзор информации о тестостероне и иммунитете: Michael P. Muehlenbein, Richard G. Bribiescas. “Testosterone-mediated Immune Functions and Male Life Histories”. American Journal of Human Biology 17, № 5 (2005).

T. W. McDade et al. “Maintenance Versus Growth: Investigating the Costs of Immune Activation Among Children in Lowland Bolivia”. American Journal of Physical Anthropology 136, № 4 (2008); Aaron D. Blackwell et al. “Life History, Immune Function, and Intestinal Helminths: Trade-offs Among Immunoglobulin E, C-reactive Protein, and Growth in an Amazonian Population”. American Journal of Human Biology 22, № 6 (2010).

Lise Aksglaede et al. “Age at Puberty and the Emerging Obesity Epidemic”. PLoS ONE 4, № 12 (2009).

A. Nuñez-de la Mora et al. “Childhood Conditions Influence Adult Progesterone Levels”. PLoS Medicine 4, № 5 (2007).

D. M. Parkin et al. “Global Cancer Statistics, 2002”. CA: A Cancer Journal for Clinicians 55, № 2 (2005).

J. E. Dunn. “Cancer Epidemiology in Populations of the United States — with Emphasis on Hawaii and California — and Japan”. Cancer Research 35, № 11 (1975); J. Lee et al. “Cancer Incidence among Korean-American Immigrants in the United States and Native Koreans in South Korea”. Cancer Control 14, № 1 (2007).

R. G. Ziegler et al. “Migration Patterns and Breast Cancer Risk in Asian-American Women”. Journal of the National Cancer Institute 85, № 22 (1993).

C. A. Lowry et al. “Identification of an Immune-responsive Mesolimbocortical Serotonergic System: Potential Role in Regulation of Emotional Behavior”. Neuroscience 146, № 2 (2007).

J. Stanford. “Successful Immunotherapy with Mycobacterium vaccae in the Treatment of Adenocarcinoma of the Lung”. European Journal of Cancer 44, № 2 (2008).

Charles L. Raison, Lucile Capuron, Andrew H. Miller. “Cytokines Sing the Blues: Inflammation and the Pathogenesis of Depression”. Trends in Immunology 27, № 1 (2006); Charles L. Raison et al. “Depressive Symptoms and Viral Clearance in Patients Receiving Interferon-alpha and Ribavirin for Hepatitis C”. Brain, Behavior and Immunity 19, № 1 (2005).

Andrew H. Miller, Vladimir Maletic, Charles L. Raison. “Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression”. Biological Psychiatry 65, № 9 (2009).

B. E. Leonard. “The Immune System, Depression and the Action of Antidepressants”. Progress in Neuro-Psychopharmacology & Biological Psychiatry 25, № 4 (2001).

Graham A. W. Rook, Christopher A. Lowry, Charles L. Raison. “Lymphocytes in Neuroprotection, Cognition and Emotion: Is Intolerance Really the Answer?” Brain, Behavior and Immunity 25, № 4 (2011).

Julie A. Pasco et al. “Association of High-sensitivity C-reactive Protein with de Novo Major Depression”. British Journal of Psychiatry 197 (2010).

M. R. Hayatbakhsh et al. “Association of Psychiatric Disorders, Asthma and Lung Function in Early Adulthood”. Journal of Asthma 47, № 7 (2010).

Michael Diamond, John P. Kelly, Thomas J. Connor. “Antidepressants Suppress Production of the Th1 Cytokine Interferon-gamma, Independent of Monoamine Transporter Blockade”. European Neuropsychopharmacology 16, № 7 (2006).

E. Naumova et al. “‘Immunogenetics of Aging’: Report on the Activities of the 15th International HLA and Immunogenetics Working Group and 15th International HLA and Immunogenetics Workshop,” Tissue Antigens 77, № 3 (2011).

Carmela Rita Balistreri et al. “LPS-Mediated Production of Pro/anti-inflammatory Cytokines and Eicosanoids in Whole Blood Samples: Biological Effects of +896A/G TLR4 Polymorphism in a Sicilian Population of Healthy Subjects”. Mechanisms of Ageing and Development 132, № 3 (2011).

Maris Kuningas et al. “Selection for Genetic Variation Inducing Pro-inflammatory Responses under Adverse Environmental Conditions in a Ghanaian Population”. PLoS ONE 4, № 11 (2009).

Lucia Malaguarnera et al. “Human Chitotriosidase Polymorphism Is Associated with Human Longevity in Mediterranean Nonagenarians and Centenarians”. Journal of Human Genetics 55, № 1 (2010).

Yu-Rong Fu et al. “Effects of Bifidobacterium bifidum on Adaptive Immune Senescence in Aging Mice”. Microbiology and Immunology 54, № 10 (2010).

A. A. Hogewoning et al. “Prevalence and Risk Factors of Inflammatory Acne Vulgaris in Rural and Urban Ghanaian Schoolchildren”. British Journal of Dermatology 161, № 2 (2009).

“Let them Eat Worms”. New Scientist, August 3, 2011.

Основано на интервью автора. Джаспер Лоуренс рассказывал свою историю на разных ресурсах. Один из сайтов: http://wormtherapy.wordpress.com/2011/01/19/the-story-of-how-i-decided-to-infect-myself-with-hookworms-andthe-founding-of-autoimmune-therapies-2-2-2/.

Джаспер Лоуренс опубликовал свою историю о поездке в Камерун здесь: http://www.kuro5hin.org/story/2006/4/30/91945/8971.

Lauren Cox. “Allergy Desperation: I’ll Take a Parasite, Please”. http://abcnews.go.com/Health/AllergiesNews/story?id=8114307&page=1&singlePage=true#.TwMqUUoyc7g.

Elizabeth Svoboda. “David Pritchard: The Worms Crawl In”. The New York Times, July 1, 2008.

Данные взяты из документов FDA, полученных по запросу в соответствии с законом о свободе информации.

Ричард Докинз. Эгоистичный ген. М.: Corpus (АСТ), АСТ, 2017.